CDP-Choline – 2-hydroxy-N,N,N-trimethylethanaminium – is a water-soluble essential nutrient that was recently named to the B-complex family of vitamins. CDP-Choline is necessary for the development and maintenance of health brain cell membranes to ensure effective signalling, structural integrity and neuronal fluidity. This nutrient is also used alongside acetic acid to synthesize acetylcholine in neurons.
Sources of choline are commonly used alongside the Racetams in nootropic stacks (such as iEnahced Core) due to their complimentary mechanisms of action. The American Institute of Medicine recommends that adults get at least 425 – 550 mg of choline in their diets every day. However, as much as 90% of the population is estimated to be deficient in this nutrient. Increasing choline intake by eating foods such as eggs, chicken, soy lecithin, wheat germ and cod fish may improve mental performance and prevent age-related cognitive decline.
Not all choline sources are made equally and as much as 50% of the choline we eat may be degraded by bacteria in the gut. Some choline supplements marketed today are known to have very low bio-availability with only a small percentage able to cross the blood-brain barrier.